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1 stars (Inferior in every way) - The Alberts text (Molecular Biology of the Cell, Fourth Edition) is superior to this text in every way. It is clearer, more precise, and contains more information. This one manages to make simple concepts become quite difficult. 5 stars (Excellent but starting to get outdated) - Excellent. Hands down the best book out there for cell biology. Gives a thorough look at the exciting unraveling of the cell. Figures are exceptional. However, being now ~3 years old and due to the intense output and growth of scientific literature this book is starting to get outdated. There have been several advances in a number of transport systems (i.e. Nuclear transport and regulation of gene expression). A new edition in the next year or so would hopefully address these issues. 1 stars (Rehash of previous edition to prevent resale.) - The book matches PERFECTLY to the previous edition... with loads of cut and paste of partial paragraphs. The result is that you could never find your way through a class using this edition with the previous edition: curbs the used book market. There is nothing more. No 'cutting edge technology' and minimal new info... not worth a new edition. All the "hard work" of putting together this edition was NOT done by the Authors, but by "hardworking" editors: NOT scientists. It isn't presenting any new science worthy of a new edition... thats just an appeal. The editing may have taken a lot of work but they obviously had a deadline! The combinations of sentences formed for the new edition from sentences edited from this and that chapter of the old edition are grammatical nightmares! The illustrations are also second rate. Why this book is popular must be a source of wonder to the editors. Half baked edition with undeserved popularity. Worse, the language hashed was difficult to begin with. A biologist who studied from this text would be a giggle to have around. ... W H Freeman :: Science & Biology :: Genetics (non-medical) :: Cellular biology :: Science&Mathematics :: Science :: Molecular biology :: Life Sciences - Cytology :: Life Sciences :: Molecular Cell Biology- Fifth Edition
5 stars (The first of its kind) - I'm giving this book a high rating because it fills a niche for which no other text exists: An absolute beginner's guide to patch-clamping. Yes, you could read Neher & Sakmann's hefty "Single Channel Recording" but, for the complete novice patch-clamper, it's a bit overwhelming. So, you walk into a patch-clamp lab, there's a million different things on the rig and you're feeling very confused. The microscope is much more complex than the microscope you remember from high school, there's cabling literally everywhere, and everybody keeps mentioning how important it is not to disturb the "voodoo" shielding. Where do you start? What do all those instruments do? Will I ever patch a cell on my own? This is the book for you. The book does an excellent job explaining the main components on a patch-clamp rig (and advice for setting up your own if you're just starting up a lab) and gives detailed instructions on whole-cell patch clamp techniques. (I have not evaluated the single-channel techniques but they too seem quite well written.) Also, many simple "equivalent circuit" diagrams are given so that you can understand what you're measuring. You will patch successfully after reading this book! My only criticism is that the book is a bit skimpy on what to do after you've got the cell patched. Only a few voltage-clamp techniques are explored and there is very little on experiments using dual recordings. Otherwise, it's an excellent book. If you're new to patch-clamping, this is (literally) the only book for you. ... John Wiley - Sons- Ltd :: Science-Research & Methodology :: Science-Life Sciences - Cytology :: Science-Life Sciences - Biochemistry :: Science :: Research & Methodology :: Life Sciences :: Patch Clamping- An Introductory Guide to Patch Clamp Electrophysiology
4 stars (Pretty Good and Basic) - This text is actually really good for beginners or as a refresher. Full of info and very detailed. 3 stars (Usefull illustrations, but it didn't help much for class) - After taking my first course in cell biology I discovered a number of things about the subject. 1) Cell Biology is a HARD CLASS! In my class, we covered about 18 or so chapters of material. Tests were based mostly on memorization of both relevant and obscure facts as well as many, many molecular processes. For someone that is pressed for time and tries to cram before tests, there will be problems. 2) It is difficult to understand many of the processes in cell biology without some chemistry background. When I took the class, I was also in organic chemistry 2, but that didn't help much. If I could have done it over again, I would actually take Biochemistry before Cell because processes in Cell Biology are explained briefly and mostly independent of the chemistry involved, which forces the student to memorize information without really understand why these processes occur. 3) In general, Biology is becoming more problem based and in order to understand cell, you need to have solve useful questions. Based on the inherent difficulties of Cell Biology that I have mentioned, I don't think that this book did much to bridge any of these learning gaps. The molecular processes were explained briefly which was ok, but since there was so many of them, it was still hard to manage. The chemistry of cell biology in this book is poorly explained. Chemical structures are largely discarded in favor of acronyms. Obvisously, acronyms are favored for the long run, but a firm understanding of the chemical structures needs to be understand first. In my opinion, this book relied too much on acroynms. Finally, the questions in this book were terrible. Some were just inane (Compare signs of life for a rock and a plant) while others were just pointless (Calculate something or the... Garland Science-Taylor -amp- Francis Group :: Biology :: Life Sciences :: Science&Mathematics :: Science :: Molecular biology :: Life Sciences - Cytology :: Life Sciences - Biology - Molecular Biology :: Life S :: Essential Cell Biology- Second Edition
5 stars (Great, but...) - I ordered this book on somewhat of a lark, and I haven't been disappointed. The material is fascinating; although so complex that even at 1,400 pages it still feels like a summary in some places, particularly the parts about RNA replication (what I'm reading right now). For self learners, it's great. I was expecting to force myself to read this thing, but I just got sucked in, reading it like a novel, although in some places it can get difficult and I find myself needing to re-read a paragraph several times. A few specific criticisms: I wish there was a better cohesion between pictures and the text. Sometimes you need to flip the page over to see the figure they reference in the text, but I'm sure that's a space concern and the book is already 1,400 pages. I'd also like to see specific pointers to papers or other books you could read if you wanted to find out more about a specific thing. Finally, the glossary is a little thin. It doesn't contain a definition for "nucleolus" for example. You might want to get a companion dictionary to go along with the book. I'd rate it more like 4.9 stars if I could. 5 stars (Molecular Biology of the Cell, Fourth Edition) - Although Molecular Biology of the Cell is suitable for specialists, it's not written exclusively for biologists. Amateur readers and those who want to expand their knowledge to one of the most interesting scientific topics, myself included, can still find the book useful and enjoyable. Starting from chapter one, the book makes use of hundreds of illustrations to explain corresponding sections. The fourth edition takes advantage of the new discoveries in genetics by expanding the material provided in previous editions. Six chapters in total have been added to expand the information on molecular genetics. Chapter one, which explains RNA Translation, the Domains of the Living World, Genetic Information in Eucaryotes, among many other things, is quite an interesting opening of ... Garland Publishing :: Cellular biology :: Science&Mathematics :: Science :: Molecular Biology :: Life Sciences - Cytology :: Life Sciences - Biology - Molecular Biology :: General :: Cyt :: Molecular Biology of the Cell- Fourth Edition
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